The Role Of Fundamental Research And Biotechnology

Resistance to antibiotics is becoming a major problem worldwide. worsen this role is the fact that few new antibiotics be in the development pipeline, and, indeed, no novel class of antibiotics has been introduced into medical practice session in more than 20 years. It is proposed that the solutions to the problem of antibiotic ohmic rampart will be found only finished primeval research that will probably use bioengineering as a tool. A variety of novel approaches being use in university laboratories and biotechnology companies are outlined. 2 approaches in particular, namely, Synsorbs and recombinant cationic peptide antimicrobials, that have been developed through the Canadian Bacterial Diseases Network, a national research consortium, are discussed. One of the major problems with valuate to antibiotic chemotherapy is that, despite the intensifier research that is being conducted by the multibillion-dollar pharmaceutical industry, no novel chemic class of antibiotics has been observed in the past 20 years [1]. Indeed, whole deep introduced antibiotic compounds are permutations (i.e., improved versions) of preexisting compounds.

Thus, a situation whereby bacterium can mutate known resistance mechanisms to set upon these improved relatives of earlier antibiotics has been created, and it is not queer for significant resistance to be observed hitherto before design of such antibiotics into the clinic [2]. One global priority must therefore be to encourage the development of novel antimicrobials, which will result in diversification of the weapons ava ilable in the war against pathogenic bacteri! a. dickens of the major limitations of this objective are the high cost ($ccc one thousand thousand per new chemical entity) of do drugs development within pharmaceutical companies and the observation that more of the large multinational companies have actually decreased their activities or compensate ceased to invest in the discovery of new antibiotics [3]. Does...If you want to light a full essay, order it on our website: OrderCustomPaper.com

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